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个人简介赵智勇老师多年来一直从事有机合成和核酸的修饰与组装调控,研究兴趣含括生物大分子(如脱氧核糖核酸DNA)与有机分子构筑的组装体的智能调控,应用于药物运载与控释体系;功能化生物大分子与无机纳米颗粒相结合,应用于癌症治疗领域;以及核酸与高分子结合构筑仿生体系,研究其结构与性能的关系等。自2011年,先后在Angew. Chem. Int. Ed.、Chem. Commun.、Small、Chem.-Eur. J.、Macromolecules 等国际权威杂志上发表SCI论文20余篇。主持国家自然科学基金青年项目、湖北省教育厅等科研项目4项。2017年10月入选湖北省“楚天学者计划”。 | ||||||
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学术成果
1. Zhao, Z.; Du, T.; Liang, F. *; Liu, S.* Amphiphilic DNA organic hybrids: Functional materials in nanoscience and potential application in biomedicine. Int. J. Mol. Sci. 2018, 19, 2283.
Kuang, S.; Hu, Z.; Zhang, H.; Zhang, X.; Liang, F.; Zhao, Z.; Liu, S.* Enhancement of metal–metal interactions inside a large-cavity synthetic host in water. Chem. Commun. 2018, 54, 2169–2172.
2. Zhao, Z.; Liang, F.; Liu, S.* Self-assembly of DNA-based Nanomaterials and Potential Application in Drug Delivery (Invited Review). Curr. Top Med. Chem. 2017, 17(16), 1829–1842.
3. Han, X.; Li, Z.; Xu, Z.; Zhao, Z.*; Liu, S.; Yin, J.* Construction of Crown Ether- Stoppering [3]Rotaxanes Based on N-Hetero Crown Ether Host. Chinese J. Chem. 2017, 35(7), 1050–1056.
4. Gong, W.; Ma, J.; Zhao, Z.; Gao, F.; Liang, F.; Zhang, H.; Liu, S.*Inhibition and Stabilization: Cucurbituril Induced Distinct Effects on the Schiff Base Reaction. J. Org. Chem. 2017, 82(6), 3298–3301.
5. Gong, W.; Yang, X.; Zavalij, P. Y.; Isaacs, L.*; Zhao, Z.; Liu S.* From Packed “Sandwich” to “Russian Doll” Assembly by Charge-Transfer Interactions in Cucurbit[10]uril (Front Cover Hot Paper). Chem. Eur. J. 2016, 22, 17612–17618.
6. Pang, T.*; Wang, H.; Wu, X.; Wu, L.; Zhao, Z.-Y.*; Wu, G.-H.* Synthesis, Crystal Structure and Fluorescence of a Bicyclic Product Containing Chromene and Propargylamine Skeleton. Chinese J. Struct. Chem. 2016, 35(8), 1277–1282.
7. Wu, F.; Song, Y.; Zhao, Z.; Zhang, S.; Yang, Z.; Li, Z.; Li, M.; Fan, Q.-H.*; Liu, D.* The Preparation and Self-assembly of Supramolecular Coil-Rod-Coil Triblock Copolymer PPO-dsDNA-PPO. Macromolecules, 2015, 48 (20), 7550–7556.
8. Zhao, Z.; Chen, C.; Dong, Y.; Yang, Z.; Fan, Q.-H.*; Liu, D.* Thermally Triggered Frame-Guided Assembly. Angew. Chem., Int. Ed., 2014, 53, 13468–13470.
9. Liu, Z.-X.; Feng, Y.*; Zhao, Z.; Yan, Z.-C.; He, Y.-M.; Luo, X.-J.; Liu, C.-Y.; Fan, Q.-H.* A New Class of Dendritic Metallogels with Multiple Stimuli-Responsiveness and as Templates for the in situ Synthesis of Silver Nanoparticles. Chem. Eur. J., 2014, 20, 533–541.
10. Zhao, Z.; Wu, F.; Yang, Z.*; Liu, D.; Fan, Q.-H.* Synthesis and Self-Assembly of DNA-Aliphatic Polyether Dendron Hybrids. Acta Chim. Sinica, 2013, 71, 549–554.
11. Zhao, Z.; Wang, L.; Liu, Y.; Yang, Z.; He, Y.-M.; Li, Z.; Fan, Q.-H.*; Liu, D.* pH-Induced Morphology-Shifting of DNA-b-Poly(propylene oxide) Assemblies. Chem. Commun., 2012, 48, 9753–9755.