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研究兴趣许娜博士长期从事生物医用材料表面纳米结构的制备和研究工作。在骨植入钛合金表面构建负载Ni、Sr、Ag等微量元素掺杂的TiO2纳米管阵列,制备了具有抗菌性和促进骨整合的表面涂层;利用Ni的催化活性,构建了高灵敏度的无酶葡萄糖电化学传感器;设计制作具有微纳结构的细胞培养基底和微流控芯片,揭示了基底对病毒在宿主细胞之间传播的分子机制。主持国家自然科学基金、湖北省自然科学基金项目等6项,参与973项目等6项国家级、省部级项目,发表论文15篇,以第一/通讯作者发表SCI收录论文7篇,申请国家发明专利2项。 | ||||
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近年研究成果
[1] Na Xu, # Hao Cheng,# Jiangwen Xu, Feng Li, Biao Gao, Zi Li, Chenghao Gao, Kaifu Huo, Jijiang Fu,* Wei Xiong*,Silver-loaded nanotubular structures enhanced bactericidal efficiency of antibiotics with synergistic effect in vitro and in vivo,International Journal of Nanomedicine,2017,12:731–743.
[2] Jiangwen Xu#, Na Xu#, Ting Zhou, Xiang Xiao, Biao Gao, Jijiang Fu⁎, Tongcun Zhang,Polydopamine coatings embedded with silver nanoparticles on nanostructured titania for long-lasting antibacterial effect,Surface & Coatings Technology,2017,320:608–613.
[3] Jiangwen Xu#, Na Xu#, Xuming Zhang, Ping Xu, Biao Gao*, Xiang Peng, Sivaprasad Mooni, Yong Li, Jijiang Fu*, Kaifu Huo,Phase separation induced rhizobia-like Ni nanoparticles and TiO2 nanowires composite arrays for enzyme-free glucose sensor,Sensors and Actuators B: Chemical, 2017, 244:38–46.
[4] Jiangwen Xu#, Na Xu#, Xuming Zhang*, Biao Gao, Ben Zhang, Xiang Peng, Jijiang Fu*, Paul K. Chu, Kaifu Huo,In situ fabrication of Ni nanoparticles on N-doped TiO2 nanowire arrays by nitridation of NiTiO3 for highly sensitive and enzyme-free glucose sensing,2017,Journal of Materials Chemistry B,2017,5,1779-1786.
[5] Min Xiao#, Na Xu#, Cheng Wang, Dai-Wen Pang,Zhi-Ling Zhang*, Dynamic monitoring of membrane nanotubes formation induced by vaccinia virus on a high throughput microfluidic chip, Scientific Reports,2017,7 :44835.
[6] Na Xu,Ji Wang,Zhen-Feng Zhang,Dai-Wen Pang,Han-Zhong Wang,Zhi-Ling Zhang*,Anisotropic cell-to-cell spread of vaccinia virus on microgrooved substrate,Biomaterials,2014,35(19):5049-5055.
[7] Na Xu,Zhen-Feng Zhang,Li Wang,Bo Gao,Dai-Wen Pang,Han-Zhong Wang,Zhi-Ling Zhang*,A microfluidic platform for real-time and in situ monitoring of virus infection process,Biomicrofluidics,2012,6(3):034122.